Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833606 | 0.81 | GAA (0.44) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL13180208 | 0.81 | ESR1 (0.45) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL9819995 | 0.78 | AGPAT2 (0.44) | KCNH2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL31500937 | 0.77 | APP (0.57) | MEN1KMT2AL3MBTL1POLB | |
| Bicarbonate SCHEMBL10758552 | 0.77 | APP (0.56) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL3640007 | 0.72 | MEN1 (0.56) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL29825622 | 0.72 | MEN1 (0.56) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL10351907 | 0.70 | HSD17B10 (0.41) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL10728044 | 0.70 | MAPT (0.68) | KCNH2GAAMEN1KMT2AKDM4E | |
| SCHEMBL27654631 | 0.69 | MAPT (0.58) | KCNH2GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-4954630-A | COLORIMETRIC OR FLUORESCENT ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-04 | — | — | US | disclosed |
| US-4737466-A | N-acyldihydroresorufin derivatives, processes for their preparation, reagents containing them and the use thereof for determining hydrogen peroxide, peroxidate-acting compounds or peroxidase | BOEHRINGER MANNHEIM GMBH (DE) | 1988-04-12 | — | — | US | disclosed |