Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819995 | 0.87 | AGPAT2 (0.44) | GAAKMT2AKCNH2MEN1LMNA | |
| SCHEMBL9296337 | 0.81 | KCNH2 (0.55) | GAAKMT2AKCNH2MEN1LMNA | |
| SCHEMBL10351907 | 0.81 | HSD17B10 (0.41) | GAAKMT2AKCNH2MEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL10351697 | 0.78 | HSD17B10 (0.37) | GAAKMT2AKCNH2MEN1LMNA | |
| B-D-Galactose SCHEMBL9819987 | 0.75 | LGALS8 (0.38) | KMT2AMEN1LMNAMAPTCASP3 | |
| Bicarbonate SCHEMBL10758552 | 0.74 | APP (0.56) | GAAKMT2AKCNH2MEN1LMNA | |
| SCHEMBL9819970 | 0.71 | MEN1 (0.42) | KMT2AMEN1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL9819961 | 0.68 | GAA (0.43) | GAAKMT2AKCNH2MEN1LMNA | |
| SCHEMBL17866889 | 0.68 | PDE10A (0.41) | GAAKMT2AMEN1CYP1A2MAPT | |
| SCHEMBL3640007 | 0.67 | MEN1 (0.56) | GAAKMT2AKCNH2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |