Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503422 | 0.86 | GABRA1 (0.46) | GABRA1GABRB2CA12CA1CA2 | |
| SCHEMBL4446113 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2POLBTYRXDH | |
| SCHEMBL69697 | 0.81 | TYR (0.58) | GABRA1GABRB2POLBTYRXDH | |
| SCHEMBL1772134 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2POLBXDHGAA | |
| SCHEMBL11115074 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2POLBTYRXDH | |
| SCHEMBL11333301 | 0.78 | HSD17B10 (0.46) | GABRA1GABRB2CA12CA1CA2 | |
| SCHEMBL28728661 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2POLBTYRXDH | |
| SCHEMBL9640862 | 0.78 | ESR1 (0.49) | GABRA1GABRB2POLBTYRXDH | |
| SCHEMBL6423969 | 0.77 | GABRA1 (0.41) | GABRA1GABRB2POLBXDHGAA | |
| SCHEMBL71514 | 0.77 | GABRA1 (0.70) | GABRA1GABRB2POLBTYRXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583300-B1 | HAIR COLOURING AGENT. | HENKEL KGAA (DE) | 1994-12-21 | — | — | EP | disclosed |
| EP-0583300-A1 | HAIR COLOURING AGENT | Henkel Kommanditgesellschaft auf Aktien (DE) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019220-A1 | HAIR COLOURING AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-11-12 | — | — | WO | disclosed |
| EP-0348849-A1 | Hairdying composition | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0176161-A1 | Novel fluoran compounds and production and use thereof | TAOKA CHEMICAL CO., LTD (JP) | 1986-04-02 | — | — | EP | disclosed |
| US-4009162-A | FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | disclosed |