SCHEMBL9296809

SCHEMBL9296809

NCc1ncc(-c2csc(N=C(N)N)n2)s1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 18/20 0.51
ATP4B P51164 18/20 0.51
NPC1 O15118 2/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 2/20 0.49
GFER P55789 1/20 0.49
TERT O14746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9298266 0.81 ATP4A (0.45) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL9298276 0.81 ATP4A (0.57) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL9296906 0.80 MAPT (0.46) ATP4AATP4BNPC1MAPTRAB9A
Bromide SCHEMBL9298167 0.80 MAPT (0.45) ATP4AATP4BNPC1MAPTRAB9A
Hydrochloric Acid SCHEMBL9298145 0.79 ATP4A (0.56) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL9298192 0.76 ATP4A (0.43) ATP4AATP4BNPC1MAPTRAB9A
Hydrochloric Acid SCHEMBL9430581 0.76 ADA (0.55) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL27325439 0.75 ATP4A (0.48) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL9298180 0.75 NPC1 (0.41) ATP4AATP4BNPC1MAPTRAB9A
SCHEMBL9298188 0.75 NPC1 (0.41) ATP4AATP4BNPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5371097-A Antiulcer agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-12-06 US disclosed
US-5364871-A Antiulcer agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-15 US disclosed
EP-0417751-A2 New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-03-20 EP disclosed