Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560433 | 0.88 | ALDH1A1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL9848814 | 0.87 | MEN1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL16943231 | 0.82 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL31679530 | 0.81 | ALDH1A1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL3913255 | 0.81 | ALDH1A1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL29868333 | 0.81 | ALDH1A1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL4664640 | 0.80 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL15155861 | 0.79 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL15584389 | 0.79 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL25695965 | 0.78 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |