Perflunafene

Perflunafene

SCHEMBL9299151

FC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C1(F)F.O=C(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793240 0.88 MEN1 (0.39) MEN1KMT2ATDP1
Perflunafene SCHEMBL7999746 0.79 MEN1 (0.53) MEN1KMT2ATDP1
Perflunafene SCHEMBL63606 0.78 MEN1 (1.00) MEN1KMT2ATDP1
Perflunafene SCHEMBL1069193 0.78 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL1279184 0.78 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL15755574 0.78 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL10889508 0.78 MEN1 (1.00) MEN1KMT2ATDP1
Perflunafene SCHEMBL63605 0.78 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL2476658 0.78 MEN1 (1.00) MEN1KMT2ATDP1
Perflunafene SCHEMBL4418110 0.78 MEN1 (1.00) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354901-A A fluorinated surfactants for low surface tension of aqueous solution MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-11 US disclosed
US-5210282-A Metal carboxylates, alcohols, acrylic esters; surfactants, elastomers, coatings, lubricants, heat transfer and cooling fluids, hydraulic fluids, vapor phase heating, oil- and waterproofing fibers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
US-5153322-A Chemical intermediates for surfactants, lubricants, coatings, hydraulic fluids, water and oil repellents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
EP-0314380-B1 PERFLUORO(CYCLOALIPHATIC METHYLENEOXYALKYLENE)CARBONYL FLUORIDES AND DERIVATIVES THEREOF MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-26 EP disclosed
US-4889656-A SURFACTANTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-26 US disclosed
EP-0314380-A1 Perfluoro(cycloaliphatic methyleneoxyalkylene)carbonyl fluorides and derivatives thereof MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-03 EP disclosed