Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299189 | 1.00 | ARG1 (0.43) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL30530817 | 0.78 | BACE1 (0.32) | ARG1SLC1A3SLC1A2SLC1A1BACE1 | |
| SCHEMBL5510070 | 0.78 | ARG1 (0.50) | ARG1CYP1A2ALOX15CYP2C19MEN1 | |
| SCHEMBL3450006 | 0.77 | CYP2D6 (0.46) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL7339053 | 0.77 | CYP2D6 (0.46) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL3450008 | 0.77 | CYP2D6 (0.46) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL9297990 | 0.75 | CYP2D6 (0.47) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL3450013 | 0.75 | CYP2D6 (0.47) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL21896074 | 0.75 | CYP2D6 (0.47) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL31688651 | 0.75 | CYP2D6 (0.47) | ARG1CYP1A2CYP2D6ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618810-A4 | BRADYKININ ANTAGONIST PEPTIDES. | SCIOS NOVA INC (US) | 1994-12-07 | — | — | EP | disclosed |
| EP-0618810-A1 | BRADYKININ ANTAGONIST PEPTIDES | SCIOS NOVA INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1992018156-A1 | BRADYKININ ANTAGONIST PEPTIDES | NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) | 1992-10-29 | — | — | WO | disclosed |