Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 11/20 | 0.52 |
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824601 | 1.00 | THRB (0.55) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL9299185 | 1.00 | THRB (0.55) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL8824606 | 1.00 | THRB (0.55) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL9299882 | 1.00 | THRB (0.55) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL22659917 | 0.92 | THRB (0.56) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL22659914 | 0.92 | THRB (0.56) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL21021147 | 0.90 | CYP2D6 (0.58) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL20820941 | 0.90 | CYP2D6 (0.58) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL16731431 | 0.90 | CYP2D6 (0.58) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL2215629 | 0.90 | CYP2D6 (0.58) | THRBCYP2D6HSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374746-A | L-talopyranoside derivatives and process for the preparation of same | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 1994-12-20 | — | — | US | disclosed |
| US-H74-H | Process for the production of 18F-2-deoxy-2-fluoro-D-glucose | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY | 1986-06-03 | — | — | US | disclosed |