Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636039 | 1.00 | NPC1 (0.51) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL8054346 | 1.00 | NPC1 (0.51) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11078052 | 0.91 | NPC1 (0.57) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL8371185 | 0.90 | NPC1 (0.50) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11630901 | 0.89 | NPC1 (0.47) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11738280 | 0.88 | ESR1 (0.50) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11528622 | 0.87 | MAPT (0.54) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11465492 | 0.84 | ALDH1A1 (0.63) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL10604190 | 0.83 | MAPT (0.50) | NPC1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL8068369 | 0.83 | MAPT (0.50) | NPC1MAPTALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296329-A | Containing acetylacetanilide coupling component | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |