Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299312 | 0.92 | TYMS (0.46) | NAMPTDHFR | |
| SCHEMBL9249466 | 0.92 | NAMPT (0.47) | NAMPTDHFR | |
| SCHEMBL5734367 | 0.89 | — | — | |
| SCHEMBL9298837 | 0.89 | NAMPT (0.43) | NAMPT | |
| SCHEMBL9246347 | 0.89 | NAMPT (0.54) | NAMPTDHFR | |
| SCHEMBL9221939 | 0.87 | HDAC1 (0.34) | — | |
| SCHEMBL8488936 | 0.86 | NAMPT (0.38) | NAMPT | |
| SCHEMBL9388379 | 0.86 | NAMPT (0.40) | NAMPT | |
| SCHEMBL8487164 | 0.85 | — | — | |
| SCHEMBL8485192 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |