Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300101 | 0.89 | PSEN1 (0.33) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9300650 | 0.87 | PPARG (0.32) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9300502 | 0.86 | PSEN1 (0.34) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9299338 | 0.85 | DUT (0.34) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9300301 | 0.85 | PDE4A (0.39) | — | |
| SCHEMBL9300855 | 0.83 | PSEN1 (0.32) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9300127 | 0.83 | PDE4A (0.39) | — | |
| SCHEMBL9299404 | 0.81 | PSEN1 (0.36) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9299657 | 0.80 | PDE4A (0.40) | — | |
| SCHEMBL9300120 | 0.80 | PSEN1 (0.33) | PPARGPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296492-A | Certain chroman derivatives useful for treating symptoms caused by contraction of smooth muscles, circulatory diseases or epilepsy | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0518342-A1 | Chroman derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-12-16 | — | — | EP | disclosed |