Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298879 | 0.84 | TNF (0.57) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL9298869 | 0.82 | TNF (0.61) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL9546914 | 0.81 | PTAFR (0.57) | TNFPTAFRCYP2C19POLBTHRB | |
| SCHEMBL9299460 | 0.81 | TNF (0.54) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL8134171 | 0.80 | TNF (0.53) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL9300153 | 0.79 | TNF (0.57) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL8129105 | 0.79 | HDAC1 (0.56) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL8137536 | 0.79 | TNF (0.59) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL8129724 | 0.78 | MMP2 (0.57) | TNFALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL9299036 | 0.78 | TNF (0.55) | TNFALDH1A1GALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276153-A | Antagonist of platelet activating factor for bronchodilation | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |