Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049547 | 0.85 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9036795 | 0.83 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9212956 | 0.82 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9049483 | 0.82 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9212964 | 0.81 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9038104 | 0.81 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9440584 | 0.81 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9300222 | 0.80 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9037817 | 0.80 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9046540 | 0.80 | ALOX5 (0.47) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334614-A | Lipoxygenase inhibitor | ZENECA LTD. (GB) | 1994-08-02 | — | — | US | disclosed |