Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061401 | 0.69 | TDP1 (0.43) | HTR2ATDP1ATMALDH1A1MAPT | |
| SCHEMBL11099610 | 0.69 | IDO1 (0.58) | HTR2AALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10643130 | 0.69 | HTR2A (0.41) | HTR2ATDP1ALDH1A1MAPTHPGD | |
| SCHEMBL11356813 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL2944428 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL10345757 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11096936 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL10346269 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL10556308 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL9168536 | 0.69 | HTR2A (0.39) | HTR2AALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340927-A | Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates | MERCK & CO., INC. (US) | 1994-08-23 | — | — | US | disclosed |