Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055291 | 0.79 | ALDH1A1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10690535 | 0.78 | HTT (0.45) | ALDH1A1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL11042629 | 0.77 | HTR2A (0.46) | ALDH1A1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL2940773 | 0.77 | MAOB (0.48) | ALDH1A1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL9871979 | 0.74 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10514009 | 0.72 | ALDH1A1 (0.50) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL2945134 | 0.70 | POLB (0.41) | ALDH1A1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL6159545 | 0.69 | TDP1 (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9300481 | 0.69 | HTR2A (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL11099610 | 0.69 | IDO1 (0.58) | ALDH1A1MAPTRAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | disclosed |