Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963232 | 0.93 | HRH3 (0.42) | KDM1AHRH3KCNH2MAOBP2RY14 | |
| SCHEMBL8963220 | 0.93 | HRH3 (0.42) | KDM1AHRH3KCNH2MAOBP2RY14 | |
| SCHEMBL8963107 | 0.89 | HDAC2 (0.40) | KDM1AKCNH2MAOBMAOAP2RY14 | |
| SCHEMBL8962800 | 0.89 | GRIA1 (0.39) | HRH3KCNH2MAOBMAOAEGLN2 | |
| SCHEMBL8962812 | 0.89 | GRIA1 (0.39) | HRH3KCNH2MAOBMAOAEGLN2 | |
| SCHEMBL8963099 | 0.89 | HDAC2 (0.40) | KDM1AKCNH2MAOBMAOAP2RY14 | |
| SCHEMBL8963065 | 0.85 | GRIA1 (0.37) | HRH3KCNH2MAOBMAOAP2RY14 | |
| SCHEMBL9300179 | 0.84 | HDAC2 (0.43) | KDM1AKCNH2MAOBMAOAHDAC2 | |
| SCHEMBL8962820 | 0.84 | HDAC2 (0.43) | KDM1AKCNH2MAOBMAOAHDAC2 | |
| SCHEMBL9475718 | 0.82 | HRH3 (0.42) | KDM1AHRH3KCNH2MAOBP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |