Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13473869 | 0.85 | TUBB4A (0.50) | NPC1RAB9ACFTRTUBB4ATUBB | |
| SCHEMBL1373668 | 0.78 | TDP1 (0.58) | RAB9ASMN1; SMN2TDP1MAPTL3MBTL1 | |
| SCHEMBL9612713 | 0.77 | GAA (0.39) | NPC1RAB9ASMN1; SMN2SDHBMAPT | |
| SCHEMBL21001740 | 0.77 | SOS1 (0.40) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL2027363 | 0.77 | PDCD1 (0.52) | PDCD1CD274NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15350245 | 0.76 | CNR2 (0.45) | PDCD1CD274NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31674204 | 0.75 | KDM4E (0.42) | RAB9ASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL1680551 | 0.75 | KMT2A (0.38) | NPC1SMN1; SMN2CFTRSDHBTDP1 | |
| SCHEMBL9909243 | 0.75 | GAA (0.46) | NPC1RAB9ASMN1; SMN2SDHBTDP1 | |
| SCHEMBL27002452 | 0.74 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |