⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046721 | 0.78 | — | — | |
| SCHEMBL3186465 | 0.76 | TSHR (0.34) | — | |
| SCHEMBL135896 | 0.76 | — | — | |
| Lithium SCHEMBL31299674 | 0.73 | — | — | |
| SCHEMBL6190992 | 0.71 | — | — | |
| SCHEMBL11784166 | 0.70 | — | — | |
| SCHEMBL11784163 | 0.70 | — | — | |
| SCHEMBL11351625 | 0.69 | TSHR (0.41) | — | |
| SCHEMBL148792 | 0.67 | — | — | |
| SCHEMBL5611405 | 0.67 | ALDH1A1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |