Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11950247 | 0.81 | TSHR (0.39) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL15233398 | 0.78 | — | — | |
| SCHEMBL869080 | 0.77 | TSHR (0.53) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL821076 | 0.77 | TSHR (0.53) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL869082 | 0.77 | TSHR (0.53) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL28064988 | 0.76 | — | — | |
| SCHEMBL13670834 | 0.76 | — | — | |
| SCHEMBL11504610 | 0.72 | — | — | |
| SCHEMBL28811213 | 0.71 | — | — | |
| SCHEMBL9442354 | 0.71 | TSHR (0.37) | TSHRCYP4F2CYP4A11HSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371237-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-12-06 | — | — | US | disclosed |
| US-5276164-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-01-04 | — | — | US | disclosed |