Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869080 | 1.00 | TSHR (0.53) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL869082 | 1.00 | TSHR (0.53) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL820772 | 0.92 | CYP4F2 (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11335823 | 0.92 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11598060 | 0.89 | — | — | |
| SCHEMBL9245608 | 0.89 | — | — | |
| SCHEMBL2427567 | 0.89 | ALDH1A1 (0.60) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL10988428 | 0.89 | — | — | |
| SCHEMBL872827 | 0.89 | — | — | |
| SCHEMBL872828 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120742-B2 | Methods of making organic compounds by metathesis | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| US-9079173-B2 | Highly Z-selective olefins metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130274482-A1 | HIGHLY Z-SELECTIVE OLEFINS METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2013-10-17 | — | — | US | disclosed |
| US-8067623-B2 | Producing waxes from soybean oil; ruthenium alkylidene catalytic, simultaneous opening and inserting | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8008224-B2 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | MATERIA, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090264672-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2009-10-22 | — | — | US | disclosed |
| US-20080064891-A1 | Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like | WILMAR TRADING PTE LTD (SG) | 2008-03-13 | — | — | US | disclosed |
| US-20070278545-A1 | Ferroelectric capacitor, method of manufacturing ferroelectric capacitor, and ferroelectric memory | SEIKO EPSON CORPORATION | 2007-12-06 | — | — | US | disclosed |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-12-06 | — | — | US | disclosed |
| EP-1863069-A2 | Ferroelectric capacitor, method of manufacturing ferroelectric capacitor, and ferroelectric memory | Seiko Epson Corporation (JP) | 2007-12-05 | — | — | EP | disclosed |
| US-20070054038-A1 | Complex oxide laminate, method of manufacturing complex oxide laminate, and device | SEIKO EPSON CORPORATION | 2007-03-08 | — | — | US | disclosed |
| EP-1760770-A2 | Complex oxide laminate, method of manufacturing complex oxide laminate, and device | SEIKO EPSON CORPORATION (JP) | 2007-03-07 | — | — | EP | disclosed |
| EP-1760768-A1 | Insulating target material, method of manufacturing insulating target material, insulating complex oxide film, and devide | Seiko Epson Corporation (JP) | 2007-03-07 | — | — | EP | disclosed |
| US-20070045109-A1 | Insulating target material, method of manufacturing insulating target material, insulating complex oxide film, and device | SEIKO EPSON CORPORATION | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264672-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | COASY, FASN, HAO2 | TSHR 4683/4885HSD17B10 46/4885MGAM 1359/4885 |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | ORC3, OXER1, CBR3 | TSHR 2215/4885HSD17B10 1888/4885MGAM 3784/4885 |
| US-20080064891-A1 | Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like | SQLE, COASY, ALOX12 | TSHR 4692/4885HSD17B10 173/4885MGAM 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.