SCHEMBL9301022

SCHEMBL9301022

Cc1cccc(NC(=O)C2CCNC2)c1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.69
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
USP2 O75604 1/20 0.54
HSD17B10 Q99714 2/20 0.51
GAA P10253 1/20 0.51
LMNA P02545 1/20 0.51
TSHR P16473 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KHK P50053 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
F10 P00742 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259381 0.93 NPSR1 (0.72) NPSR1NPC1RAB9AUSP2GAA
SCHEMBL259383 0.91 NPSR1 (0.78) NPSR1NPC1RAB9AUSP2HSD17B10
SCHEMBL10192117 0.85 NPSR1 (0.88) NPSR1NPC1RAB9AUSP2HSD17B10
SCHEMBL6037575 0.84 ALDH1A1 (0.52) NPSR1LMNAKDM4EALDH1A1KHK
SCHEMBL14505992 0.83 HPGD (0.60) NPC1RAB9AGAALMNAKDM4E
SCHEMBL1318504 0.83 HPGD (0.60) NPC1RAB9AGAALMNAKDM4E
SCHEMBL23951327 0.83 F10 (0.62) USP2HSD17B10GAATSHRKHK
SCHEMBL30098450 0.83 F10 (0.62) USP2HSD17B10GAATSHRKHK
SCHEMBL12764072 0.82 NPSR1 (0.94) NPSR1NPC1RAB9AUSP2GAA
SCHEMBL13920562 0.82 NPSR1 (1.00) NPSR1NPC1RAB9AUSP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5278034-A Color development agent FUJI PHOTO FILM CO., LTD. (JP) 1994-01-11 US disclosed