Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299791 | 1.00 | PDPK1 (0.65) | PDPK1MTORTSHRBCHESSTR1 | |
| SCHEMBL9706801 | 0.88 | PDPK1 (0.52) | PDPK1MTORTSHRBCHESSTR1 | |
| SCHEMBL9706806 | 0.88 | PDPK1 (0.52) | PDPK1MTORTSHRBCHESSTR1 | |
| SCHEMBL7775231 | 0.83 | PDPK1 (0.45) | PDPK1MTORTSHRBCHESSTR1 | |
| SCHEMBL10626765 | 0.81 | PDPK1 (0.60) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL10626759 | 0.81 | PDPK1 (0.60) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL9155090 | 0.81 | PDPK1 (0.60) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL25362771 | 0.80 | SSTR1 (0.54) | PDPK1MTORBCHESSTR1SSTR2 | |
| SCHEMBL20107395 | 0.80 | SSTR1 (0.54) | PDPK1MTORBCHESSTR1SSTR2 | |
| SCHEMBL7152150 | 0.80 | SSTR1 (0.54) | PDPK1MTORBCHESSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371203-A | Reacting a triester of L-fucose with trichloroacetonitrile to form corresponding trichloroacetimidate, followed by phosphating,hydrogenolysis, deprotecting, salt formation; a substrate for fucosyltransferases; tumor diagnosis | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-12-06 | — | — | US | disclosed |