SCHEMBL9301232

C[C@@H]1C[C@H](OC(=O)NC(C)(C)C)[C@@]2(C)CC[C@H]3[C@@H](CC[C@H]4N(C)C(=O)CC[C@]34C)[C@H]12

nearest known ligand 0.59

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A2	P31213	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8650498	0.88	SRD5A1 (0.48)	SRD5A2
SCHEMBL8650495	0.88	SRD5A1 (0.48)	SRD5A2
SCHEMBL8651170	0.81	SRD5A2 (0.48)	SRD5A2
SCHEMBL8722314	0.80	SRD5A2 (0.51)	SRD5A2
SCHEMBL8721517	0.80	SRD5A2 (0.51)	SRD5A2
SCHEMBL8646976	0.79	SRD5A2 (0.49)	SRD5A2
SCHEMBL8646979	0.79	SRD5A2 (0.49)	SRD5A2
SCHEMBL8651214	0.78	SRD5A1 (0.53)	SRD5A2
SCHEMBL8651217	0.78	SRD5A1 (0.53)	SRD5A2
SCHEMBL8651280	0.78	SRD5A1 (0.53)	SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5359071-A	Selective antagonist of testosterone 5-alpha-reductase 1	MERCK & CO., INC. (US)	1994-10-25	—	—	US	disclosed