Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650498 | 1.00 | SRD5A1 (0.48) | SRD5A1SRD5A2 | |
| SCHEMBL9301232 | 0.88 | SRD5A2 (0.54) | SRD5A2 | |
| SCHEMBL8925438 | 0.84 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL8651214 | 0.82 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8651280 | 0.82 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8939839 | 0.82 | AR (0.33) | — | |
| SCHEMBL8651217 | 0.82 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8646976 | 0.81 | SRD5A2 (0.49) | SRD5A2 | |
| SCHEMBL8646979 | 0.81 | SRD5A2 (0.49) | SRD5A2 | |
| SCHEMBL8650013 | 0.80 | SRD5A1 (0.53) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | claimed |
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0700291-A4 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0700291-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO. INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5359071-A | Selective antagonist of testosterone 5-alpha-reductase 1 | MERCK & CO., INC. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994020104-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO, INC. (US) | 1994-09-15 | — | — | WO | disclosed |