SCHEMBL9301254

SCHEMBL9301254

Cc1cccc(C(CN)c2cccc(C)c2C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 6/20 0.40
ADRA2A P08913 4/20 0.40
ADRA2B P18089 4/20 0.40
ADRA2C P18825 4/20 0.40
ADRA1A P35348 3/20 0.40
ADRA1B P35368 3/20 0.40
TSHR P16473 3/20 0.40
ADRA1D P25100 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
KCNH2 Q12809 1/20 0.40
TP53 P04637 1/20 0.40
CYP2C19 P33261 1/20 0.40
TAAR1 Q96RJ0 4/20 0.39
HTR2A P28223 2/20 0.39
SLC6A2 P23975 1/20 0.39
HTR7 P34969 1/20 0.39
TRPA1 O75762 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10578683 0.83 HRH1 (0.43) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL516440 0.82 ESR1 (0.48) SCN4AADRA2AADRA2BADRA1ATSHR
SCHEMBL3826707 0.81 SCN4A (0.39) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL5610783 0.80 ADRA2A (0.41) ADRA2AADRA2BADRA2CADRA1AADRA1B
Hydrochloric Acid SCHEMBL28611572 0.79 ADRA2A (0.40) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL15656392 0.78 ADRA2A (0.40) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL10822146 0.77 FFAR1 (0.41) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL14144720 0.76 SCN4A (0.40) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL11628180 0.76 SCN4A (0.36) SCN4AADRA2AADRA2BADRA2CADRA1A
SCHEMBL2413915 0.75 HTR2A (0.42) SCN4AADRA2AADRA2BADRA2CADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300528-A Use of perfluoroethyldimethyl cyclohexane for oxygen transport AIR PRODUCTS AND CHEMICALS, INC. (US) 1994-04-05 US disclosed
EP-0521492-A2 Perfluoro (ethyldimethylcyclohexane) AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-01-07 EP disclosed
US-5146014-A Perfluoroethyldimethyl cyclohexane AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-09-08 US disclosed
US-4801761-A VAPOR PHASE SOLDERING FLUIDS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-01-31 US disclosed