Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.78 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pobilukast SCHEMBL29473536 | 0.88 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL125952 | 0.88 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL6437479 | 0.88 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL9508133 | 0.87 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL9508139 | 0.87 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9855869 | 0.83 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MAPTRXFP1BID | |
| SCHEMBL9855870 | 0.83 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MAPTRXFP1BID | |
| SCHEMBL9428622 | 0.83 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MAPTRXFP1BID | |
| Pobilukast SCHEMBL635997 | 0.83 | CYSLTR2 (0.89) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9560386 | 0.83 | CYSLTR2 (0.74) | CYSLTR2CYSLTR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276044-A | For topical application having enhanced effectiveness and decreased irritancy | ALLERGAN, INC. (US) | 1994-01-04 | — | — | US | disclosed |