Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.69 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.69 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855869 | 1.00 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9427841 | 0.87 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9427834 | 0.87 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9428622 | 0.86 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9429001 | 0.85 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364855 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364859 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9428107 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9856022 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9301491 | 0.83 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | claimed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |