Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenylalanine Methyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine Methyl Ester SCHEMBL9356083 | 1.00 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL4996192 | 0.97 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL14988957 | 0.94 | MEN1 (0.57) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL186022 | 0.93 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL27880854 | 0.93 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL74887 | 0.93 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL74888 | 0.93 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL136409 | 0.92 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL2237414 | 0.92 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL136408 | 0.92 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109847455-B | Composite material for filtering fine particles, preparation method and application thereof | 四川大学 | 2021-07-06 | — | — | CN | claimed |
| CN-119899373-A | (-) -Gossypol derivative and preparation method thereof and antioxidant | 武汉轻工大学 | 2025-04-29 | — | — | CN | disclosed |
| CN-109847455-B | Composite material for filtering fine particles, preparation method and application thereof | 四川大学 | 2021-07-06 | — | — | CN | disclosed |
| EP-0376230-B1 | Preparation and isolation of mineral acid salt of an amino methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-11-23 | — | — | EP | disclosed |
| EP-0334236-B1 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5113009-A | PREPARATION AND ISOLATION OF MINERAL ACID SALT OF AN AMINO ACID METHYL ESTER | MITSUI TOATSU CHEMICALS, INCORPORATED | 1992-05-12 | — | — | US | disclosed |
| EP-0376230-A2 | Preparation and isolation of mineral acid salt of an amino methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0334236-A2 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-27 | — | — | EP | disclosed |