Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.83 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.83 |
| ▸ | RELA | Q04206 | 1/20 | 0.83 |
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301589 | 1.00 | FPR2 (0.83) | FPR2NFKB1NFKB2RELAPPARG | |
| SCHEMBL3406945 | 0.93 | FPR2 (0.92) | FPR2NFKB1NFKB2RELAPPARG | |
| SCHEMBL3299698 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| SCHEMBL1692159 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| Lipoxin A4 SCHEMBL19668574 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| Lipoxin A4 SCHEMBL1691709 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| Lipoxin A4 SCHEMBL3408493 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| SCHEMBL12102087 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| Lipoxin A4 SCHEMBL3302874 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG | |
| Lipoxin A4 SCHEMBL8743448 | 0.91 | FPR2 (1.00) | FPR2NFKB1NFKB2RELAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097059-A2 | Skin treatment compositions | UNILEVER N.V. (NL) | 1983-12-28 | — | — | EP | claimed |
| US-5342976-A | Long chain omega-hydroxy fatty acid or a carboxy-substituted derivative; imparts barrier function to prevent moisture loss | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5202357-A | Skin barrier | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-4950688-A | CONTROLLING SKIN BARRIER FUNCTION; HYDROXY FATTY ACID OR ESTER | CONOPCO, INC. (US) | 1990-08-21 | — | — | US | disclosed |