Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GPR174 | Q9BXC1 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258598 | 0.89 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL22716822 | 0.89 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9847721 | 0.86 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9303323 | 0.86 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL2976815 | 0.85 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL20061844 | 0.85 | DCTPP1 (0.47) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL30258446 | 0.85 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL521293 | 0.85 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL22724915 | 0.83 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL2982396 | 0.83 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |