SCHEMBL9301787

SCHEMBL9301787

CCC1(c2ccccc2)C(=O)NC(=O)N(CCCCC(=O)NCCCNC(=O)CCC(=O)OC2CC(=O)NC2=O)C1=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.41
LMNA P02545 2/20 0.39
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
DRD2 P14416 4/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803894 0.98 CYP2C19 (0.40) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7813714 0.94 CYP2C19 (0.39) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7524932 0.87 CYP2C19 (0.42) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7773269 0.84 CYP2C19 (0.50) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7776780 0.82 NPC1 (0.44)
SCHEMBL9301792 0.82 SMN1; SMN2 (0.43) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7769133 0.80 LMNA (0.51) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7776791 0.80 CYP2C19 (0.52) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL7769114 0.80 CYP2C19 (0.46) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL9301436 0.80 SMN1; SMN2 (0.45) CYP2C19LMNAKMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5284948-A Drug hapten analogues for immunoassays EASTMAN KODAK COMPANY (US) 1994-02-08 US claimed