Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302580 | 0.91 | ALDH1A1 (0.52) | GRIN1GRIN2BF10MAPTALDH1A1 | |
| SCHEMBL6171495 | 0.82 | GAA (0.59) | GRIN1GRIN2BMAPTALDH1A1NPC1 | |
| SCHEMBL9302827 | 0.82 | MAPT (0.71) | GRIN1GRIN2BMAPTALDH1A1NPC1 | |
| SCHEMBL7916738 | 0.79 | GRIN1 (0.85) | GRIN1GRIN2BF10CYP1A2CYP2E1 | |
| SCHEMBL9672269 | 0.78 | GRIN1 (0.46) | GRIN1GRIN2BF10CYP1A2CYP2E1 | |
| SCHEMBL9671495 | 0.78 | GRIN1 (0.57) | GRIN1GRIN2BF10CYP1A2CYP2E1 | |
| SCHEMBL7518814 | 0.77 | GRIN1 (1.00) | GRIN1GRIN2BF10CYP1A2CYP2E1 | |
| SCHEMBL11458535 | 0.77 | KMT2A (0.63) | CYP1A2CYP3A4CYP2C19MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11903456 | 0.76 | GRIN1 (0.65) | GRIN1GRIN2BF10CYP1A2CYP2E1 | |
| SCHEMBL3995236 | 0.76 | ALDH1A1 (0.53) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |