Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301995 | 1.00 | BDKRB1 (0.53) | BDKRB1CCKBR | |
| SCHEMBL9301992 | 1.00 | BDKRB1 (0.53) | BDKRB1CCKBR | |
| SCHEMBL8824649 | 0.99 | BDKRB1 (0.54) | BDKRB1CCKBR | |
| SCHEMBL8824648 | 0.99 | BDKRB1 (0.54) | BDKRB1CCKBR | |
| SCHEMBL8824652 | 0.99 | BDKRB1 (0.54) | BDKRB1CCKBR | |
| SCHEMBL9302412 | 0.94 | BDKRB1 (0.45) | BDKRB1CCKBR | |
| SCHEMBL9302403 | 0.94 | BDKRB1 (0.45) | BDKRB1CCKBR | |
| SCHEMBL9302408 | 0.94 | BDKRB1 (0.45) | BDKRB1CCKBR | |
| SCHEMBL9302341 | 0.89 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9302348 | 0.89 | CCKBR (0.54) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |