Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.57 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 9/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302006 | 1.00 | BDKRB1 (0.57) | BDKRB1SENP1CCKBR | |
| SCHEMBL9302001 | 1.00 | BDKRB1 (0.57) | BDKRB1SENP1CCKBR | |
| SCHEMBL8824775 | 0.99 | BDKRB1 (0.58) | BDKRB1SENP1CCKBR | |
| SCHEMBL8824772 | 0.99 | BDKRB1 (0.58) | BDKRB1SENP1CCKBR | |
| SCHEMBL8824769 | 0.99 | BDKRB1 (0.58) | BDKRB1SENP1CCKBR | |
| SCHEMBL9218957 | 0.98 | BDKRB1 (0.55) | BDKRB1SENP1CCKBR | |
| SCHEMBL9218964 | 0.98 | BDKRB1 (0.55) | BDKRB1SENP1CCKBR | |
| SCHEMBL9218953 | 0.98 | BDKRB1 (0.55) | BDKRB1SENP1CCKBR | |
| SCHEMBL9303321 | 0.93 | SENP1 (0.56) | BDKRB1SENP1CCKBR | |
| SCHEMBL9303317 | 0.93 | SENP1 (0.56) | BDKRB1SENP1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |