Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.53 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.46 |
| ▸ | CCKBR | P32239 | 7/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008788 | 1.00 | SENP1 (0.53) | SENP1BDKRB1CCKBROXTRSCN9A | |
| SCHEMBL9302112 | 1.00 | SENP1 (0.53) | SENP1BDKRB1CCKBROXTRSCN9A | |
| SCHEMBL9301274 | 1.00 | SENP1 (0.53) | SENP1BDKRB1CCKBROXTRSCN9A | |
| SCHEMBL9008787 | 1.00 | SENP1 (0.53) | SENP1BDKRB1CCKBROXTRSCN9A | |
| SCHEMBL9008789 | 1.00 | SENP1 (0.53) | SENP1BDKRB1CCKBROXTRSCN9A | |
| SCHEMBL9303317 | 0.89 | SENP1 (0.56) | SENP1BDKRB1CCKBRSCN9ABRD4 | |
| SCHEMBL9701052 | 0.89 | SENP1 (0.56) | SENP1BDKRB1CCKBRSCN9ABRD4 | |
| SCHEMBL9303321 | 0.89 | SENP1 (0.56) | SENP1BDKRB1CCKBRSCN9ABRD4 | |
| SCHEMBL8824772 | 0.89 | BDKRB1 (0.58) | SENP1BDKRB1CCKBR | |
| SCHEMBL8824775 | 0.89 | BDKRB1 (0.58) | SENP1BDKRB1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |