Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302223 | 0.88 | KDM4E (0.41) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9301465 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL9304165 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL9302393 | 0.85 | KDM4E (0.38) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9303155 | 0.85 | HRH3 (0.38) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL9302026 | 0.82 | DRD3 (0.44) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL9301963 | 0.79 | ALDH1A1 (0.36) | CRBNALDH1A1DRD3KDM4ELMNA | |
| SCHEMBL9303487 | 0.77 | HDAC1 (0.34) | — | |
| SCHEMBL9847726 | 0.76 | KDM4E (0.40) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL29634202 | 0.75 | TSHR (0.33) | ALDH1A1KDM4EMAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |