Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302033 | 0.82 | HPGD (0.60) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9302149 | 0.77 | AR (0.55) | PTAFRMEN1KMT2APOLBHPGD | |
| SCHEMBL9303110 | 0.77 | PTAFR (0.52) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL18924427 | 0.76 | KDM4E (0.56) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9302077 | 0.76 | AR (0.55) | PTAFRMEN1KMT2APOLBLMNA | |
| SCHEMBL9301867 | 0.75 | SMN1; SMN2 (0.53) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9303194 | 0.74 | PTAFR (0.48) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9303440 | 0.73 | HPGD (0.51) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9302140 | 0.72 | SMN1; SMN2 (0.47) | PTAFRMEN1KMT2AITKPOLB | |
| SCHEMBL9302074 | 0.72 | PTAFR (0.46) | PTAFRMEN1KMT2AITKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |