Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302077 | 0.94 | AR (0.55) | ARPTAFRMEN1KMT2APOLB | |
| SCHEMBL9301665 | 0.89 | AR (0.53) | ARMEN1KMT2APOLBAPEX1 | |
| SCHEMBL9302033 | 0.82 | HPGD (0.60) | PTAFRMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9302594 | 0.81 | AR (0.55) | ARPTAFRMEN1KMT2APOLB | |
| SCHEMBL9302140 | 0.80 | SMN1; SMN2 (0.47) | PTAFRMEN1KMT2APOLBAPEX1 | |
| SCHEMBL9302074 | 0.79 | PTAFR (0.46) | PTAFRMEN1KMT2APOLBAPEX1 | |
| SCHEMBL9302162 | 0.79 | SMN1; SMN2 (0.47) | PTAFRMEN1KMT2APOLBAPEX1 | |
| SCHEMBL9302215 | 0.78 | PTAFR (0.44) | PTAFRMEN1KMT2APOLBAPEX1 | |
| SCHEMBL9303110 | 0.77 | PTAFR (0.52) | PTAFRMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9302224 | 0.77 | PTAFR (0.52) | PTAFRMEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |