SCHEMBL9302230

SCHEMBL9302230

CSc1cc2c(cc1C#Cc1cnc(CCCCC(=O)O)nc1)C(SC)(SC)CCO2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.31
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667778 0.89 NPC1 (0.31)
SCHEMBL6664862 0.88 CYP26A1 (0.30)
SCHEMBL9301905 0.86 PTGER4 (0.38) PTGER4
SCHEMBL9302621 0.86
SCHEMBL9302094 0.82
SCHEMBL9304106 0.81 NPC1 (0.33)
SCHEMBL7654888 0.79 NPC1 (0.31)
SCHEMBL9302758 0.79 FFAR1 (0.38) PTGER4FFAR1
SCHEMBL9301245 0.77
SCHEMBL7650613 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354752-A A dimethylthiochroman or dimethylchroman-6-yl-ethynyl-pyridazin- or pyrimidin- or pyrazin-for treating skin disorders psoriasis ALLERGAN, INC. (US) 1994-10-11 US claimed