Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.34 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 3/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671507 | 0.89 | RXRA (0.37) | FFAR1RXRAHNF4ARARARARB | |
| SCHEMBL6664727 | 0.87 | CYP26A1 (0.40) | FFAR1RXRAHNF4ACYP26A1CYP26B1 | |
| SCHEMBL9303121 | 0.85 | RXRA (0.34) | FFAR1RXRAHNF4ACYP26A1CYP26B1 | |
| SCHEMBL9301731 | 0.85 | CYP26A1 (0.41) | RXRAHNF4ACYP26A1CYP26B1PTGER4 | |
| SCHEMBL9139409 | 0.85 | RXRA (0.37) | FFAR1RXRAHNF4ARARARARB | |
| SCHEMBL9139432 | 0.84 | RXRA (0.34) | FFAR1RXRAHNF4ACYP26A1CYP26B1 | |
| SCHEMBL6669202 | 0.81 | RXRA (0.37) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9302221 | 0.81 | CYP3A4 (0.43) | FFAR1RXRACYP26A1CYP26B1RARA | |
| SCHEMBL7649079 | 0.81 | TBXAS1 (0.31) | RARARARBRARG | |
| SCHEMBL9301379 | 0.80 | RXRA (0.40) | RXRAHNF4ACYP26A1CYP26B1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354752-A | A dimethylthiochroman or dimethylchroman-6-yl-ethynyl-pyridazin- or pyrimidin- or pyrazin-for treating skin disorders psoriasis | ALLERGAN, INC. (US) | 1994-10-11 | — | — | US | claimed |