Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304259 | 0.87 | GALR3 (0.69) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL1160088 | 0.85 | POLB (0.51) | GALR3NR2F2RAB9APOLBTNF | |
| SCHEMBL9301970 | 0.83 | GALR3 (0.57) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL6169405 | 0.81 | POLB (0.49) | POLBTNFALDH1A1HPGDTSHR | |
| SCHEMBL8137536 | 0.81 | TNF (0.59) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL18535200 | 0.80 | GALR3 (0.72) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL9303635 | 0.80 | LMNA (0.59) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL9298879 | 0.80 | TNF (0.57) | GALR3NR2F2RAB9APOLBTNF | |
| SCHEMBL9302805 | 0.79 | TNF (0.53) | GALR3NR2F2RAB9ATNFALDH1A1 | |
| SCHEMBL8129105 | 0.79 | HDAC1 (0.56) | GALR3NR2F2RAB9ATNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |