SCHEMBL9302378

SCHEMBL9302378

C=C(C)C(=O)OC(C)CC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301201 0.87 TSHR (0.37) TSHRALDH1A1
SCHEMBL9304046 0.87 TSHR (0.37) TSHRALDH1A1
SCHEMBL8699662 0.87 TSHR (0.39) TSHRALDH1A1
SCHEMBL9301691 0.83 TSHR (0.39) TSHRALDH1A1
SCHEMBL15421826 0.83 TSHR (0.39) TSHRALDH1A1
SCHEMBL1954842 0.83 TSHR (0.36) TSHRALDH1A1
SCHEMBL14760250 0.82 TSHR (0.34) TSHR
SCHEMBL17049378 0.81 TSHR (0.35) TSHR
SCHEMBL2540758 0.78 TSHR (0.50) TSHRALDH1A1
SCHEMBL8465842 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11427666-B2 Silicone-containing acrylic polymers for transdermal drug delivery compositions NOVEN PHARMACEUTICALS, INC. (US) 2022-08-30 US disclosed
US-20200277424-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2020-09-03 US disclosed
EP-3179989-B1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMA (US) 2019-06-12 EP disclosed
EP-3179989-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS Noven Pharmaceuticals, INC. (US) 2017-06-21 EP disclosed
WO-2016018858-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 WO disclosed
US-20160030362-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 US disclosed
US-5376378-A Transdermal drug delivery CIBA-GEIGY CORP. (US) 1994-12-27 US disclosed
US-5288827-A Drug selivery CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed