SCHEMBL9302411

SCHEMBL9302411

C=C(C)C(=O)OC(C)C(C)[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302924 0.86 TSHR (0.40) TSHRALDH1A1
SCHEMBL9303133 0.86 TSHR (0.36) TSHRALDH1A1
SCHEMBL4734217 0.76 TSHR (0.50) TSHRALDH1A1
SCHEMBL5177443 0.76 TSHR (0.50) TSHRALDH1A1
SCHEMBL9302018 0.75 TSHR (0.36) TSHRALDH1A1
SCHEMBL1273966 0.74 TSHR (0.35) TSHRALDH1A1
SCHEMBL4738203 0.74 TSHR (0.35) TSHRALDH1A1
SCHEMBL9820071 0.73 TSHR (0.37) TSHRALDH1A1
SCHEMBL8966142 0.72 TSHR (0.46) TSHRALDH1A1
SCHEMBL11053273 0.72 TSHR (0.46) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11427666-B2 Silicone-containing acrylic polymers for transdermal drug delivery compositions NOVEN PHARMACEUTICALS, INC. (US) 2022-08-30 US disclosed
US-20200277424-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2020-09-03 US disclosed
EP-3179989-B1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMA (US) 2019-06-12 EP disclosed
EP-3179989-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS Noven Pharmaceuticals, INC. (US) 2017-06-21 EP disclosed
WO-2016018858-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 WO disclosed
US-20160030362-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 US disclosed
US-5376378-A Transdermal drug delivery CIBA-GEIGY CORP. (US) 1994-12-27 US disclosed