SCHEMBL9820071

SCHEMBL9820071

C=C(C)C(=O)OC(C)[Si](C)(O)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25329223 0.80 TSHR (0.42) TSHRALDH1A1
SCHEMBL3886364 0.78 TSHR (0.43) TSHRALDH1A1
SCHEMBL145421 0.78 TSHR (0.43) TSHRALDH1A1
SCHEMBL5394202 0.75 TSHR (0.41) TSHRALDH1A1
SCHEMBL6925919 0.73 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL16537575 0.73 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL9303133 0.73 TSHR (0.36) TSHRALDH1A1
SCHEMBL9302924 0.73 TSHR (0.40) TSHRALDH1A1
SCHEMBL2028634 0.73 TSHR (0.36) TSHRALDH1A1
SCHEMBL9302411 0.73 TSHR (0.36) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0215817-B1 CONTINUOUS-WEAR LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP disclosed