Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304312 | 0.91 | CCKBR (0.68) | CCKBRBDKRB1 | |
| SCHEMBL9302475 | 0.91 | CCKBR (0.81) | CCKBRBDKRB1 | |
| SCHEMBL9701102 | 0.91 | CCKBR (0.78) | CCKBRBDKRB1 | |
| SCHEMBL9302718 | 0.90 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9302428 | 0.86 | CCKBR (0.85) | CCKBR | |
| SCHEMBL9303107 | 0.85 | CCKBR (0.81) | CCKBRBDKRB1 | |
| SCHEMBL9301932 | 0.82 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9701151 | 0.82 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9304288 | 0.82 | CCKBR (0.84) | CCKBR | |
| SCHEMBL9008742 | 0.82 | BDKRB1 (0.75) | CCKBRBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |