Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881710 | 0.99 | GAA (0.71) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| SCHEMBL9302456 | 0.86 | GAA (0.65) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| Potassium Ion SCHEMBL9302501 | 0.84 | GAA (0.63) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| SCHEMBL16147252 | 0.83 | ALDH1A1 (0.62) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| SCHEMBL10475479 | 0.83 | GAA (0.66) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| SCHEMBL7274899 | 0.83 | ALDH1A1 (0.68) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| Aminomethylbenzoic Acid SCHEMBL4199661 | 0.83 | ALDH1A1 (0.53) | GAAHPGDPKMSMN1; SMN2ALDH1A1 | |
| Bendazol SCHEMBL309393 | 0.83 | GAA (1.00) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| Bendazol SCHEMBL29539948 | 0.83 | GAA (1.00) | GAAHPGDPKMSMN1; SMN2GRIN1 | |
| SCHEMBL6165378 | 0.83 | F2 (0.69) | GAAHPGDPKMSMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |