Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301613 | 0.85 | PTAFR (0.50) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9302156 | 0.82 | PTAFR (0.48) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9302869 | 0.82 | PTAFR (0.48) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9305054 | 0.81 | PTAFR (0.47) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9301794 | 0.81 | HSD11B1 (0.48) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9301925 | 0.81 | PTAFR (0.47) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9301708 | 0.80 | HSD11B1 (0.47) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9302761 | 0.80 | PDK2 (0.47) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9303513 | 0.80 | HPGD (0.49) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9303318 | 0.78 | PTAFR (0.45) | PTAFRHSD11B1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |