Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339013 | 0.84 | ELANE (0.83) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL269329 | 0.83 | LMNA (0.80) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL5831549 | 0.82 | ELANE (0.67) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL5831547 | 0.82 | ELANE (0.67) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL9762610 | 0.82 | ELANE (0.67) | ELANEHSD17B10LMNAMAPTPOLB | |
| 4-(Acetate)Acetophenone SCHEMBL1142839 | 0.82 | MAPT (0.67) | ELANEHSD17B10LMNAMAPTPOLB | |
| Lithium SCHEMBL30522746 | 0.81 | LMNA (0.76) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL14760365 | 0.81 | LMNA (0.76) | ELANEHSD17B10LMNAMAPTPOLB | |
| SCHEMBL40184 | 0.80 | HSD17B10 (0.88) | ELANEHSD17B10LMNAMAPTPOLB | |
| 4-(Acetate)Acetophenone SCHEMBL28047084 | 0.80 | ELANE (0.64) | ELANEHSD17B10LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332811-A | Antitumor intermediates | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-07-26 | — | — | US | disclosed |