Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497107 | 0.87 | HDAC1 (0.70) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL9302980 | 0.87 | CYP11B1 (0.62) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL1608602 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL10467944 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL10467889 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL10468260 | 0.83 | TP53 (0.70) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL10469085 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL9304028 | 0.82 | TNF (0.51) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL9303216 | 0.82 | TNF (0.51) | SMN1; SMN2RECQLMAPK10HDAC1HDAC6 | |
| SCHEMBL1750364 | 0.81 | HDAC1 (0.73) | SMN1; SMN2HDAC1HDAC6CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | claimed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |