Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.50 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.50 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085846 | 0.88 | IDO1 (0.64) | CYP11B1CYP11B2ALDH1A1IDO1MAPK10 | |
| SCHEMBL9302833 | 0.87 | SMN1; SMN2 (0.73) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL10467937 | 0.87 | SMN1; SMN2 (0.47) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL10468107 | 0.87 | CYP4F2 (0.48) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL1608602 | 0.85 | SMN1; SMN2 (0.60) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL2885662 | 0.83 | CYP11B1 (0.67) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL9304028 | 0.81 | TNF (0.51) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL9303216 | 0.81 | TNF (0.51) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL9301804 | 0.80 | SMN1; SMN2 (0.50) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL12531261 | 0.80 | CYP11B1 (0.74) | CYP11B1CYP11B2ALDH1A1IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |